Wernicke Encephalopathy

An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3)

Also Known As:

Wernicke's Encephalopathy; Wernicke Syndrome; Encephalopathy, Gayet-Wernicke; Encephalopathy, Wernicke's; Gayet-Wernicke Encephalopathy; Wernicke Disease; Wernicke Polioencephalitis, Superior Hemorrhagic; Wernicke Superior Hemorrhagic Polioencephalitis; Wernicke's Disease; Wernicke's Polioencephalitis, Superior Hemorrhagic; Wernicke's Superior Hemorrhagic Polioencephalitis; Wernicke's Syndrome; Cerebral Beriberi; Encephalopathies, Wernicke; Encephalopathy, Gayet Wernicke; Encephalopathy, Wernickes; Gayet Wernicke Encephalopathy; Wernicke Encephalopathies; Beriberi, Cerebral; Encephalopathy, Wernicke

Nervous System Diseases: 14178
- Central Nervous System Diseases: 4213
  - Brain Diseases: 15694
    - Metabolic Brain Diseases: 215
      - Wernicke Encephalopathy: 667
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Metabolic Brain Diseases: 215
    - Wernicke Encephalopathy: 667
- Nutrition Disorders: 404
  - Malnutrition: 20403
    - Deficiency Diseases: 514
      - Avitaminosis: 1294
        Vitamin B Deficiency: 65
        Thiamine Deficiency: 1103
        Wernicke Encephalopathy: 667
Chemically-Induced Disorders: 2
- Substance-Related Disorders: 21181
  - Alcohol-Related Disorders: 548
    - Wernicke Encephalopathy: 667
Mental Disorders: 24177
- Substance-Related Disorders: 21181
  - Alcohol-Related Disorders: 548
    - Wernicke Encephalopathy: 667

Ken Koguchi Selected Research

Ken Koguchi Research Topics

Disease

Drug/Important Bio-Agent (IBA)